Triple-Negative Breast Cancer: Valerie's Survivor Story

This breast cancer diagnosis at a glance

Biomarkers
Triple-negative breast cancer; ER-negative; PR-negative; HER2-negative
Sex
Female
Treatment
chemotherapy, surgery and radiation
Outcome
Survivorship / Surveillance

Treatment course, step by step

  1. Chemotherapy before surgery to shrink a large locally advanced triple-negative breast tumor
  2. lumpectomy instead of mastectomy after strong response
  3. radiation therapy. Specific chemotherapy drugs and radiation schedule are not stated.

What happened, in summary

Valerie Hamilton was 56 when she was diagnosed with locally advanced triple-negative breast cancer. The tumor was large, and doctors outside MSK had told her she would need a mastectomy. That possibility felt overwhelming: Valerie loved her body and worried about how surgery and recovery would affect her life as a wife, mother, church member and teacher of 10th-grade special-needs students. At Memorial Sloan Kettering, her surgeon believed there might be another path. Instead of going straight to mastectomy, Valerie received chemotherapy before surgery to shrink the tumor. The approach worked very well. Her tumor shrank enough that she could have a less invasive lumpectomy rather than a mastectomy. Radiation therapy followed surgery. Chemotherapy drug names, the radiation schedule and a formal stage number were not provided beyond the cancer being described as locally advanced. No explicit no-evidence-of-disease status was provided. Her treatment centered on preserving both cancer control and her sense of self. Through treatment and recovery, she remained connected to her husband, family, church and students, and she did not lose the sense of herself that she had feared cancer would take away.

Where this story comes from

This is a lay summary of an account first published by Memorial Sloan Kettering. Read the original in full

How we source and attribute stories Accuracy and limitations

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