Triple-Negative Breast Cancer: Mariann's Survivor Story

This breast cancer diagnosis at a glance

Biomarkers
Triple-negative breast cancer
Sex
Female
Treatment
surgery and reconstruction
Outcome
Cancer-Free / NED

Treatment course, step by step

  1. Double mastectomy for triple-negative breast cancer, followed by implant reconstruction
  2. Later implant replacements did not improve tightness, pulling, cold implants, or low sensation
  3. Cleveland Clinic consultation in 2016 explored reconstruction using her own tissue
  4. 11.5-hour DIEP reconstruction used abdominal tissue, with artery and nerve reconnection to restore blood flow and sensation
  5. About 2 years later, sensation and natural feel had improved.

What happened, in summary

Mariann Lotenero was treated for triple-negative breast cancer with a double mastectomy at a California hospital. Afterward, she was deeply grateful to be alive and said she did not have cancer anymore, but survivorship brought a different problem. Her reconstructed breasts had very little sensation, the implants felt cold even in warm weather, and she often felt tightness and pulling in her chest. Later implant replacements did little to improve how she felt. During a Cleveland Clinic follow-up visit in 2016, Dr. Holly Pederson referred Mariann to plastic surgeon Dr. Risal Djohan, who specialized in autologous breast reconstruction. He offered a DIEP free flap procedure, using fat, skin and tissue from the lower abdomen to rebuild the breasts. His approach also involved reconnecting arteries and nerves from the abdominal tissue to the chest to restore blood flow and potentially allow sensation to return as nerve fibers regenerated. Mariann chose to try reconstruction one more time. The operation lasted 11.5 hours and was successful. Slowly, as she healed, sensation began returning. As of October 2019, about 2 years after the free flap surgery and about 6 years after cancer treatment, Mariann said she looked and felt normal again and sometimes forgot she had cancer.

Where this story comes from

This is a lay summary of an account first published by Cleveland Clinic. Read the original in full

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