Stage IV Triple-Negative Breast Cancer: Maggie's Survivor Story

This breast cancer diagnosis at a glance

Stage at diagnosis
Stage IV
Biomarkers
ER-negative; PR-negative; HER2-negative (triple-negative)
Sex
Female
Spread to
lungs, lymph nodes; possible liver
Treatment
a clinical trial, chemotherapy and immunotherapy
Outcome
Cancer-Free / NED

Treatment course, step by step

  1. Taxol was first discussed before U.S. treatment
  2. Testing showed PD-L1 positivity, which opened the option of chemotherapy plus immunotherapy
  3. After getting her green card, she entered a clinical trial
  4. Trial treatment included 2 years of chemotherapy plus CT scan monitoring, often with treatments on Fridays.

What happened, in summary

Maggie was applying for a U.S. green card when she was diagnosed in 2022 with de novo Stage IV triple-negative breast cancer. She is from the Netherlands and had planned to move to the United States because her wife is American. Before the diagnosis, she noticed a large bruised feeling in her left breast but brushed it off because the area felt soft and she did not think breast cancer fit her situation.

A pulmonary specialist quickly pushed her to get a mammogram after seeing something concerning in the breast area. Mammogram and biopsy confirmed breast cancer, and the cancer had already spread to lymph nodes and the lungs; she also recalled possible liver involvement. The tumor was triple-negative, and she later learned she was PD-L1 positive, which opened the door to immunotherapy.

Taxol was initially discussed, but once Maggie reached the United States, her oncologist moved quickly to enroll her in a clinical trial. The trial involved chemotherapy plus immunotherapy, with treatment often on Fridays and 2 years of chemotherapy and CT scans covered by the sponsor. Side effects included fatigue, trouble eating or drinking after treatment, nausea, and heartburn. As of February 2025, Maggie reported being cancer-free, with no evidence of disease for well over 1 year.

Where this story comes from

This is a lay summary of an account first published by The Patient Story. Read the original in full

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