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A 34-year-old woman was diagnosed with metastatic invasive lobular breast cancer during pregnancy. Treatment began while she was still pregnant, and she received 5 cycles of docetaxel.
After 4 cycles, imaging showed a near-complete response. Her treatment plan was then adapted for the period after delivery. As soon as it was clinically feasible postpartum, she started trastuzumab and pertuzumab together with tamoxifen.
During the first postpartum treatment cycle, breast milk was collected for 17 days, until lactation stopped. Testing found measurable transfer of trastuzumab and pertuzumab into breast milk, supporting the recommendation not to breastfeed during this treatment.
Her cancer had shown a near-complete response to chemotherapy during pregnancy, and systemic treatment continued after delivery.
This is a lay summary of an account first published by PMC / PubMed Central. Read the original in full
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These are lay summaries of published cancer stories, for information only. No two cancers behave the same way, and nothing here predicts your own diagnosis or replaces advice from your oncology team. Read the full disclaimer