Stage II Triple-Negative Breast Cancer: Italia's Survivor Story

This breast cancer diagnosis at a glance

Stage at diagnosis
Stage II
Biomarkers
ER-negative; PR-negative; HER2-negative (triple-negative); BRCA mutation
Sex
Female
Treatment
chemotherapy, surgery and immunotherapy
Outcome
Cancer-Free / NED

Treatment course, step by step

  1. BRCA testing in July 2023 showed increased breast cancer risk
  2. mammogram, ultrasound and biopsy after breast lump in August 2023
  3. Stage II triple-negative breast cancer diagnosed September 19, 2023
  4. chemotherapy from October 2023 through April 2024
  5. May 2024 double mastectomy with Goldilocks reconstruction
  6. immunotherapy ongoing at the story update, with 3 infusions remaining.

What happened, in summary

Italia Russell was 30 when she found a breast lump in August 2023, 1 month after learning she carried a BRCA mutation that increased her lifetime breast cancer risk. Her mother had been treated 15 years earlier for Stage II triple-negative breast cancer and had also tested positive for BRCA, so Italia knew she wanted care at Cleveland Clinic Weston Hospital. She traveled from Freeport, Grand Bahama, to Florida for mammogram, ultrasound, and biopsy. On September 19, 2023, Italia was diagnosed with Stage II triple-negative breast cancer. She stayed near Weston with an aunt while receiving chemotherapy from October 2023 through April 2024. Because treatment weakened her immune system, she could not fly home to see her husband and family during that period. In May 2024, she had a double mastectomy to remove unhealthy breast tissue. During the same operation, she had a Goldilocks reconstruction, which uses remaining healthy skin and fat to shape the breast area. Italia also received immunotherapy as part of her care and still had 3 infusions left as of the story update. Her body responded well to chemotherapy: by the time of surgery, the tumor was gone. As of October 2024, Italia had no evidence of disease and was encouraging others to complete recommended genetic testing.

Where this story comes from

This is a lay summary of an account first published by Cleveland Clinic. Read the original in full

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