Right-Breast DCIS Found Alongside a Separate Malignant Phyllodes Tumor

This breast cancer diagnosis at a glance

Subtype
Invasive Ductal Carcinoma
Biomarkers
ER-positive, PR-positive, HER2-negative
Sex
female
Treatment
surgery and endocrine therapy
Outcome
Cancer-Free / NED

Treatment course, step by step

  1. Underwent right mastectomy as part of a bilateral mastectomy.
  2. Started endocrine therapy after discharge.

What happened, in summary

A 79-year-old woman was found to have tumors in both breasts. The right-breast lesion measured about 2.8 cm on MRI, and core biopsy showed ductal carcinoma in situ. A right sentinel lymph-node biopsy was negative, and staging scans found no distant disease.

She underwent bilateral mastectomy because of the synchronous tumors. The right-breast specimen confirmed low- to intermediate-grade ductal carcinoma in situ. The DCIS was strongly estrogen- and progesterone-receptor positive and HER2-negative. After discharge, she began endocrine therapy.

At the same operation, the separate large tumor in the left breast was confirmed as a malignant phyllodes tumor. At 18 months of follow-up, there were no concerning clinical or imaging changes, no enlarged axillary or supraclavicular lymph nodes, and no suspicious lung nodules. The right-sided DCIS therefore remained without documented recurrence at the latest follow-up.

Where this story comes from

This is a lay summary of an account first published by PMC / PubMed Central. Read the original in full

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