Rare Triple-Negative Mucinous Cystadenocarcinoma of the Breast

This breast cancer diagnosis at a glance

Biomarkers
Triple-negative
Sex
Female
Treatment
chemotherapy and surgery
Outcome
Responding Well

Treatment course, step by step

  1. Received neoadjuvant doxorubicin and cyclophosphamide.
  2. Underwent left subcutaneous mastectomy with sentinel lymph node biopsy.

What happened, in summary

A 34-year-old woman developed persistent discharge from her left nipple and a growing breast mass. Imaging initially suggested an abscess, and her symptoms temporarily improved with antibiotics. When the discharge became bloody and the mass enlarged toward the skin, biopsy showed an invasive breast cancer with a triple-negative profile.

Because the tumor had unusual mucin-producing features, further pathology was needed to determine whether it was truly a primary breast cancer or a metastasis from another organ. The final surgical pathology supported primary mucinous cystadenocarcinoma of the breast, a very rare breast-cancer subtype. One sentinel lymph node contained a large cancer deposit, while the second had isolated tumor cells; no confirmed distant metastatic site was established.

She received neoadjuvant doxorubicin and cyclophosphamide and then underwent a left subcutaneous mastectomy with sentinel lymph-node biopsy. Genetic testing did not provide a simple actionable explanation for the tumor. At 6-month follow-up, she was alive and well.

Where this story comes from

This is a lay summary of an account first published by PMC / PubMed Central. Read the original in full

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