Stage 4 ALK Positive Lung Cancer: 53 Real Stories

Stage IV ALK Lung Cancer: Shyreece's Patient Story

Patient Info: Shyreece Pompey, Female | Stage IV

Biomarkers: ALK-positive mutation identified by FISH testing

As of March 2022, Shyreece was living and advocating nearly 8 years after being diagnosed with Stage IV ALK-positive lung cancer; this segment does not report treatment response or a remission/NED status.

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Alectinib restored vision from an eye metastasis of ALK-positive lung cancer

Patient Info: Anonymized, Male, 60s | Stage IV

Biomarkers: ALK-positive.

Metastatic Site: right choroid of the eye; liver; bone; brain

After nearly eight months of response to alectinib, the lung cancer progressed in the liver, bone, and brain; lorlatinib was started, but he died on July 3, 2020.

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Stage IV ALK Non-Small Cell Lung Cancer: James's Patient Story

Patient Info: James “Rocky” Lagno, Male | Stage IV

Biomarkers: ALK-positive

Metastatic Site: brain

After starting ceritinib through compassionate use, Rocky reported stable disease from the middle of 2013 with quality of life close to his pre-diagnosis level, while recognizing that he was not in remission or cancer-free.

Stage IV ALK Lung Adenocarcinoma: Amanda's Survivor Story

Patient Info: Amanda Nerstad, Under 40 | Stage IV

Biomarkers: ALK-positive

She achieved a complete metabolic response on alectinib and had shown no evidence of disease since November 2017 while continuing treatment.

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Delayed Adrenal Insufficiency After Nivolumab for Stage IV Lung Cancer

Patient Info: Anonymized, Male, 70+ | Stage IV

Biomarkers: EGFR unmutated; ALK unmutated; ROS1 unmutated

His weakness, fatigue, weight loss, and orthostatic hypotension resolved after hormone replacement, and he returned home independently.

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