Radiation for ER Positive Breast Cancer: 125 Real Stories

Metastatic lobular breast cancer to gynecologic sites: disease-free after surgery and chemotherapy

Patient Info: Anonymized, Female, 50s | Stage IV

Biomarkers: ER-positive; PR-negative; HER2/C-Erb-B2-negative

Metastatic Site: vagina, uterus, ovaries

After treatment of vaginal, uterine, and ovarian metastases from lobular breast cancer, she was free from disease 12 months after completion surgery.

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Hormone-positive breast cancer with axillary recurrence responding to hyperthermia, radiation, and chemotherapy

Patient Info: Anonymized, Female, 60s

Biomarkers: ER-positive; PR-positive; HER2-negative

The left axillary recurrence enlarged during weekly paclitaxel and radiotherapy, then became nearly flat and was assessed as a complete response 8 weeks after adding hyperthermia.

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Metastatic lobular breast cancer to bladder trigone: partial response to tamoxifen

Patient Info: Anonymized, Female, 60s | Stage IV

Biomarkers: progesterone receptor-positive; genetic testing including BRCA1 negative

Metastatic Site: bladder trigone

As of January 2012, urge incontinence had resolved and PET showed decreased activity in the breast and bladder trigone lesions nearly 10 months after starting tamoxifen, consistent with clinical and partial radiologic remission.

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Lobular breast cancer with extraocular muscle and lung metastases: ocular improvement after radiotherapy and tamoxifen

Patient Info: Anonymized, Female, 60s | Stage IV

Biomarkers: Original breast cancer: ER-negative; PR-negative. Extraocular muscle metastasis/recurrent disease: ER strongly positive; PR strongly positive.

Metastatic Site: bilateral extraocular muscles, right upper lobe lung,…

At 18 months after presentation with extraocular muscle metastases, PET showed no abnormality, diplopia had resolved, and ocular motility had markedly improved, with mild bilateral ptosis remaining.

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ER-positive breast cancer recurrence after DCIS: chemotherapy, nodal surgery, radiation, and endocrine therapy

Patient Info: Anonymized, Female, 40s

Biomarkers: Recurrent invasive breast cancer: ER-positive; HER2/neu-negative. PR not reported.

Disease-free for 33 months after treatment of ER-positive, HER2-negative invasive breast cancer recurring in the mastectomy skin flap with positive axillary sentinel nodes.

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