Stage IV Invasive Lobular Carcinoma: Kris's Patient Story

Patient Info: Kris, Female | Stage IV

Metastatic Site: Bone | Bone marrow | Stomach

Kris was diagnosed in 2019 with occult de novo Stage IV ILC after endoscopy biopsy showed breast cancer in the stomach, with disease described in the bone, bone marrow, and stomach from skull to femurs.

Lobular Breast Cancer AllianceRead more →

Stage IV HR-Positive Invasive Lobular Carcinoma: Leanne's Patient Story

Patient Info: Leanne, Female, 50s | Stage IV

Biomarkers: ER-positive; PR-positive; HER2-positive

Metastatic Site: Brain

Leanne was first diagnosed in 2015 with Stage III triple-positive ILC and then diagnosed with metastatic lobular breast cancer with brain metastasis on April 4, 2018, causing major neurologic and work limitations.

Lobular Breast Cancer AllianceRead more →

Stage IV HER2-Positive Non-Small Cell Lung Cancer: Glenna's Survivor Story

Patient Info: Glenna, Female | Stage IV

Biomarkers: HER2 mutation confirmed by blood and tissue biopsy biomarker testing

Stage IV HER2-mutated NSCLC with first-line chemotherapy failure, then ongoing Enhertu from September 2023 and official NED/no evidence of disease status.

Lung Cancer Research FoundationRead more →

Stage IV ALK Lung Cancer: Elizabeth's Patient Story

Patient Info: Elizabeth Moir, Female, Under 40 | Stage IV

Biomarkers: ALK mutation / ALK-positive

Metastatic Site: Liver; bones

Elizabeth passed away on August 27, 2021 at age 32 from complications of Stage IV ALK-positive lung cancer, after earlier achieving a July 2019 scan with no evidence of disease on oral targeted therapy.

Lung Cancer Research FoundationRead more →

Stage IV EGFR Non-Small Cell Lung Cancer: Lexi's Patient Story

Patient Info: Lexi, Female, Under 40 | Stage IV

Biomarkers: EGFR exon 20 mutation

Metastatic Site: Bone — left leg and hip

Living with Stage IV EGFR exon 20 metastatic NSCLC involving bone, after chemotherapy, targeted therapy, a drug trial, and surgery to remove the primary lung mass; latest disease-control status is not clearly stated.

Lung Cancer Research FoundationRead more →

Stage IV EGFR Non-Small Cell Lung Cancer: Bill's Patient Story

Patient Info: Bill, Male | Stage IV

Biomarkers: EGFR exon 21 mutation

Metastatic Site: Spine; brain; hips/bone

Stage IV EGFR exon 21 lung cancer improved in brain and spine on osimertinib, but later lung-mass growth led to clinical-trial treatment; Bill remained active in advocacy and felt positive about progress.

Lung Cancer Research FoundationRead more →

Stage IV ALK Non-Small Cell Lung Cancer: Suzanne's Patient Story

Patient Info: Suzanne, Female | Stage IV

Biomarkers: ALK mutation identified on tissue biopsy; blood biomarker test was negative

Metastatic Site: Not specified

Stage IV ALK-positive lung cancer was stable for almost 4 years on alectinib before progression in mid-2023; Suzanne moved to brigatinib and radiation and was working toward stability again.

Lung Cancer Research FoundationRead more →

Stage IV ALK Non-Small Cell Lung Cancer: Donna's Patient Story

Patient Info: Donna Preston, Female | Stage IV

Biomarkers: ALK mutation

Metastatic Site: Not specified

Living nearly 9 years after a January 2015 Stage IV ALK-positive lung cancer diagnosis, with ongoing targeted therapy and good functional status; exact drug name is not reported.

Lung Cancer Research FoundationRead more →

Stage IV Lung Cancer: Hakim's Patient Story

Patient Info: Hakim Rusli, Male | Stage IV

Metastatic Site: Brain

Stage IV lung cancer with brain metastasis became controlled after care at Modern Cancer Hospital Guangzhou; progression slowed and symptoms/supportive issues were managed, but no remission or NED status is reported.

Stage IV ALK Non-Small Cell Lung Cancer: Marley's Patient Story

Patient Info: Marley, Female | Stage IV

Biomarkers: ALK-positive

Metastatic Site: Chest lymph nodes; axillary lymph nodes; lymph nodes…

Living with Stage IV ALK-positive NSCLC involving lymph nodes and malignant pleural fluid, with scans every 3 months; specific treatment regimen is not reported.

Lung Cancer Research FoundationRead more →

Stage IV Lung Cancer: Mila's Patient Story

Patient Info: Mila Gardon, Female, 50s | Stage IV

Metastatic Site: Neck lymph nodes; skull; iliac bone

Stage IV lung cancer with spread to neck lymph nodes, skull, and iliac bone responded after cryotherapy and interventional therapy; lung tumors disappeared and tumor marker normalized, but the source does not state full remission or NED.

Stage IV Lung Cancer: Xavier's Patient Story

Patient Info: Xavier Sanders, Male | Stage IV

Metastatic Site: Liver; brain; lymph nodes

Living with Stage IV lung cancer involving lymph nodes, liver, and 20 to 30 brain tumors while advocating for service members and caregiver support; exact treatment regimen is not reported.

Lung Cancer Research FoundationRead more →

Stage IV ALK Non-Small Cell Lung Cancer: Linnea's Patient Story

Patient Info: Linnea Olson, Female, 40s | Stage IV

Biomarkers: ALK mutation / ALK-rearranged lung cancer

Metastatic Site: Lungs / intrapulmonary disease

Living long term with Stage IV ALK-positive NSCLC; ALK-targeted clinical trials controlled disease for years but were described as disease control rather than cure.

Massachusetts General HospitalRead more →

Stage IV Lung Cancer: Tejal's Patient Story

Patient Info: Tejal, Female | Stage IV

Metastatic Site: Not specified

Living with Stage IV lung cancer and advocating against stigma while raising awareness and research funding; treatment, biomarkers, and disease-control status are not reported.

Lung Cancer Research FoundationRead more →

Stage IV ALK Lung Cancer: Jay's Survivor Story

Patient Info: Jay Petri, Male | Stage IV

Biomarkers: ALK mutation / ALK-rearranged lung cancer

Metastatic Site: Not reported

Stage IV ALK-positive lung cancer treated through clinical trials at Mass General; he reported being cancer-free for nearly 1.5 years after going through 3 trials.

Massachusetts General HospitalRead more →

Stage IV Non-Small Cell Lung Cancer: Amy's Patient Story

Patient Info: Amy, Female | Stage IV

Metastatic Site: Neck lymph node; bones — hips, femurs, foot; adrenal…

Living 5 years after Stage IV squamous NSCLC diagnosis, after Keytruda did not work and treatment included bone radiation, SBRT to the lung nodule, and adrenal cryoablation.

Lung Cancer Research FoundationRead more →

Stage IV HR-Positive Breast Cancer: Robbie's Patient Story

Patient Info: Robbie, Female | Stage IV

Biomarkers: Estrogen receptor-positive / ER-positive

Metastatic Site: Bone; liver

Living with metastatic breast cancer involving bone and liver after earlier DCIS and Stage II ER-positive breast cancer; ongoing treatment at Mass General focused on stabilization and long-term disease management.

Massachusetts General HospitalRead more →

Stage IV EGFR Non-Small Cell Lung Cancer: Gerri's Patient Story

Patient Info: Gerri, Female | Stage IV

Biomarkers: EGFR-positive / EGFR-mutated

Metastatic Site: Not reported

Living actively with Stage IV EGFR-positive NSCLC after wedge resection and unnamed EGFR-directed targeted therapy, with major hiking and travel goals continuing after diagnosis.

Lung Cancer Research FoundationRead more →

Stage IV Colorectal Cancer: Gwen's Survivor Story

Patient Info: Gwen Powell, Female | Stage IV

Biomarkers: Biomarker testing performed; results not reported

Metastatic Site: Ovary; liver

Stage IV colon cancer with ovarian mass and liver metastasis treated with chemotherapy and surgeries including colostomy/reversal; she reported being almost 2 years NED while living with neuropathy and surveillance anxiety.

Fight Colorectal CancerRead more →

Stage IV KRAS Non-Small Cell Lung Cancer: Maureen's Patient Story

Patient Info: Maureen, Female | Stage IV

Biomarkers: KRAS mutation

Metastatic Site: Not reported

Living with KRAS-mutated Stage IV lung cancer after initial Stage I diagnosis, later surgery, and radiation, while remaining active in KRAS and lung cancer advocacy.

Lung Cancer Research FoundationRead more →

Stage IV Colorectal Cancer: Amber's Survivor Story

Patient Info: Amber Madden, Female, 40s | Stage IV

Biomarkers: Comprehensive hereditary cancer genetic testing negative; tumor biomarkers not reported

Metastatic Site: Liver

Stage III colon cancer upstaged to Stage IV after liver metastasis was found; after colectomy, chemotherapy, liver surgery, and more chemotherapy, CT scans in May, August, and November 2025 showed no evidence of active cancer.

Fight Colorectal CancerRead more →

Stage IV Lung Cancer: Karen's Patient Story

Patient Info: Karen, Female, 40s | Stage IV

Biomarkers: Rare mutation affecting about 3% of lung cancer patients; mutation not named

Metastatic Site: Rib/bone involvement reported through recurrent tumor…

More than 8 years after initial Stage II lung cancer, Karen had a Stage IV recurrence requiring removal of a tumor and 2 ribs; she remained active and hopeful, but ongoing targeted treatment is not specifically stated.

Lung Cancer Research FoundationRead more →

Sydney Stoner: Stage IIIB to Stage IV colon cancer with liver and lung involvement

Patient Info: Sydney Stoner, Female, Under 40 | Stage IV

Metastatic Site: Liver; lungs

Progressed from Stage IIIB colon cancer to Stage IV disease involving the liver and lungs; treated with surgery/ileostomy/reversal, FOLFOX/FOLFIRI, lung radiation, liver ablation/resection, capecitabine, and ongoing Lonsurf + Avastin.

Fight Colorectal CancerRead more →

Laura Greco: Stage IV Lung Cancer

Patient Info: Laura Greco, Female | Stage IV

Biomarkers: ALK translocation / ALK-driven; MET amplification; EGFR amplification reported in brain tumor

Metastatic Site: Brain

Laura Greco passed away on July 14, 2024 after Stage IIIA ALK-driven lung cancer later metastasized to the brain and required repeated brain-directed treatment and targeted therapy.

Lung Cancer Research FoundationRead more →