Stage 4: 1,129 Real Stories

1,129 stories match stage 4. 777 of them mention chemotherapy.

Cancer Stories

Shawn, who was diagnosed with Stage IV Colorectal CancerColorectal Cancer

Shawn: Stage IV Colorectal Cancer

Patient Info: Shawn, Male, 40s | Stage IV

As of February 2025, Shawn had completed surgery for Stage IV colorectal cancer and was preparing to begin chemotherapy while recovering physically and emotionally.

The Patient Story
OutcomeCare Ongoing
Shawn, who was diagnosed with Stage IV Colorectal CancerColorectal Cancer

Stage IV Colorectal Cancer: Shawn's Patient Story

Patient Info: Shawn Michael, Male, 40s | Stage IV

Metastatic Site: liver, spleen, lung

Recovering from emergency surgery for Stage IV colorectal cancer involving the liver, spleen, and lung, with systemic chemotherapy and additional specialist treatment planned. As of February 2025, he was actively managing metastatic disease.

The Patient Story
OutcomeCare Ongoing
A patient, who was diagnosed with Stage IV Breast CancerBreast Cancer

Stage 4 hormone receptor-positive breast cancer: remission with PARP inhibitor

Patient Info: Anonymized, Female, 40s | Stage IV

Biomarkers: HR-positive breast cancer with HER2-low/negative recurrence, and pathogenic BRCA2 R2318* mutation.

Metastatic Site: pleura

As of January 2025, she had maintained complete response for 36 months after sequential FEC/docetaxel and olaparib for hormone receptor-positive, HER2-negative/HER2-low metastatic breast cancer with BRCA2 R2318* mutation.

PubMed Central
OutcomeCancer-Free / NED
A patient, who was diagnosed with Stage IV Non-Small Cell Lung CancerLung Cancer

Advanced Non-Small Cell Lung Cancer With ERBB2 and TP53 Mutations

Patient Info: Anonymized, male, 50s | Stage IV

Biomarkers: ERBB2 exon 20 Y772-A775dup mutation; TP53 mutation; PD-L1 TPS 0%

Metastatic Site: liver, bone, both lungs

Imaging after treatment showed stable disease, and he remained in good condition while continuing maintenance pemetrexed and bevacizumab.

PubMed Central
OutcomeStable Disease
A patient, who was diagnosed with Stage IV Small Cell Lung CancerLung Cancer

ALK-Fusion Small Cell Lung Cancer Responding to ALK-Targeted Therapy

Patient Info: Anonymized, female, 40s | Stage IV

Biomarkers: EML4-ALK fusion

Metastatic Site: brain

After several earlier treatments stopped controlling the cancer, ALK-targeted iruplinalkib produced a partial response and was still controlling disease after more than 8 months.

PubMed Central
OutcomeResponding Well
Shayla, who was diagnosed with Stage IV Colorectal CancerColorectal Cancer

Stage IV Colorectal Cancer: Shayla's Patient Story

Patient Info: Shayla, Female, Under 40 | Stage IV

Metastatic Site: Liver

As of February 2025, Shayla was in ongoing treatment for Stage IV colorectal cancer with liver metastasis after 4 rounds of chemotherapy, liver resection, and resumed chemotherapy.

The Patient Story
OutcomeCare Ongoing
Lindy, who was diagnosed with Stage IV Colorectal CancerColorectal Cancer

Stage IV Colorectal Cancer: Lindy's Patient Story

Patient Info: Lindy, Female, Under 40 | Stage IV

Metastatic Site: Lymph nodes; liver; lungs

As of February 2025, Lindy was living with treatable but incurable Stage IV colon cancer involving lymph nodes, liver, and lungs, with good response to chemotherapy and ongoing maintenance treatment.

The Patient Story
OutcomeResponding Well
Eugenia, who was diagnosed with Stage IV Non-Small Cell Lung CancerLung Cancer

Stage IV Non-Small Cell Lung Cancer: Eugenia's Patient Story

Patient Info: Eugenia Horan, Female, 40s | Stage IV

Eugenia became Stage IV while critically ill in the ICU and was later told hospice might be appropriate, but she started Keytruda on August 29, 2019 and was alive 5 years later. As of February 2025, she described that treatment as the medicine that saved her.

The Patient Story
OutcomeResponding Well
Nicola, who was diagnosed with Stage IV Colorectal AdenocarcinomaColorectal Cancer

Stage IV Colorectal Adenocarcinoma: Nicola's Survivor Story

Patient Info: Nicola, Female | Stage IV

Biomarkers: BRAF: wild-type / non-BRAF colorectal adenocarcinoma

Metastatic Site: Brain

As of January 2025, Nicola had been in remission for 9 months after treatment for Stage IV colorectal cancer with brain metastasis and remained under high-risk monitoring.

The Patient Story
OutcomeCancer-Free / NED
Mark, who was diagnosed with Stage IV Gastric CancerGastric Cancer

Stage IV Gastric Cancer: Mark's Patient Story

Patient Info: Mark Scragg, male, Under 40 | Stage IV

Biomarkers: Lynch syndrome

After 3 months of chemotherapy and immunotherapy, scans showed no sign of the stomach tumor. By the 2025 article, Mark had finished active treatment, felt well, and his cancer was described as remaining largely in remission.

Dana-Farber
OutcomeResponding Well
A patient, who was diagnosed with Stage IV Lung AdenocarcinomaLung Cancer

Metastatic Lung Adenocarcinoma With a Serious Immune-Therapy Pituitary Complication

Patient Info: Anonymized, male, 60s | Stage IV

Biomarkers: No detected EGFR, ALK, ROS1, RET, MET or HER2 alterations

Metastatic Site: brain, meninges, skull, bone, pituitary

The cancer had progressed to extensive brain, skull and bone involvement after several treatments. Steroid treatment improved the severe thirst, high urine output and other symptoms from immune-related hypophysitis.

PubMed Central
OutcomeSetback / Progression
Emily, who was diagnosed with Stage IV Colorectal CancerColorectal Cancer

Stage IV HER2-Positive Colorectal Cancer: Emily's Patient Story

Patient Info: Emily King, Female, Under 40 | Stage IV

Biomarkers: HER2-positive

Metastatic Site: lungs

Emily remained on active treatment for metastatic HER2-positive colon cancer, and her current Boston treatment had shrunk the cancer by 20% with fewer side effects.

The Patient Story
OutcomeResponding Well
Nicola, who was diagnosed with Stage IV Colorectal AdenocarcinomaColorectal Cancer

My COLON CANCER Spread to My Brain!

Patient Info: Nicola, Female | Stage IV

Metastatic Site: brain

Nicola described a clear brain MRI after craniotomy and radiation and said she was 9 months in remission, while remaining on high-risk surveillance.

The Patient Story
OutcomeCancer-Free / NED
A patient, who was diagnosed with Stage IV Small Cell Lung CancerLung Cancer

Stage IV small cell lung cancer: no abnormality after chemotherapy, radiotherapy, and TCM follow-up

Patient Info: Anonymized, Male, 60s | Stage IV

Metastatic Site: bilateral lungs; left supraclavicular lymph nodes;…

After chemotherapy, radiotherapy, supportive care, and longitudinal TCM follow-up, imaging showed disappearance of the main lung, nodal, and intrapulmonary lesions, with no abnormality found after 4 years of follow-up.

PubMed Central
OutcomeCancer-Free / NED
Rachael, who was diagnosed with Stage IV Colorectal CancerColorectal Cancer

How I Found Out I Had Stage 4 Colon Cancer!

Patient Info: Rachael Marie, Female, Under 40 | Stage IV

Metastatic Site: ovaries, liver

Rachael completed 12 cycles of FOLFOX/oxaliplatin; colonoscopy looked clear, liver lesions had shrunk, and no new lesions were reported, with further surgical planning pending.

The Patient Story
OutcomeResponding Well
Rachael, who was diagnosed with Stage IV Colorectal CancerColorectal Cancer

Stage IV Colorectal Cancer: Rachael's Patient Story

Patient Info: Rachael, Female, Under 40 | Stage IV

Metastatic Site: Ovaries; liver

As of January 2025, Rachael had completed intensive chemotherapy for Stage IV sigmoid colon cancer involving the ovaries and liver and was awaiting scans to determine whether liver surgery and HIPEC would be next.

The Patient Story
OutcomeCare Ongoing
Roshonda, who was diagnosed with Stage IV Colorectal CancerColorectal Cancer

Stage IV Colorectal Cancer: Roshonda's Patient Story

Patient Info: Roshonda, Female | Stage IV

Metastatic Site: Lung

As of January 2025, Roshonda was living after treatment for Stage IV rectal cancer with a lung spot, including chemoradiation, IV chemotherapy, and permanent colostomy surgery.

The Patient Story
OutcomeCare Ongoing
Roshonda, who was diagnosed with Stage IV Colorectal CancerColorectal Cancer

Stage IV Colorectal Cancer: Roshonda's Survivor Story

Patient Info: Roshonda Clark, Female, 40s | Stage IV

Roshonda completed chemoradiation and permanent-colostomy surgery, returned to work, and described living day by day with recurrence worries but no active treatment reported.

The Patient Story
OutcomeSurvivorship / Completed Treatment
A patient, who was diagnosed with Stage IV Lung Squamous Cell CarcinomaLung Cancer

Stage IV Squamous Lung Cancer Complicated by an Esophageal-Mediastinal Fistula

Patient Info: Anonymized, male, 70+ | Stage IV

Metastatic Site: brain, bone

Four months after the fistula was treated conservatively, imaging showed the fistula had resolved and the lung tumor and metastatic hilar nodes had decreased despite no additional antitumor treatment during that interval.

PubMed Central
OutcomeResponding Well
A patient, who was diagnosed with Stage IV Small Cell Lung CancerLung Cancer

Small Cell Lung Cancer With Rapidly Progressive Paraneoplastic Neuropathy

Patient Info: Anonymized, male, 50s | Stage IV

Metastatic Site: adrenal glands

Despite a partial tumor response, severe ascending motor and sensory neuropathy progressed to respiratory compromise. He chose supportive care and died 3 weeks after the neurologic symptoms began.

PubMed Central
OutcomeIn Memory